Role of Gut Microbiome in Cardiovascular Health
The gut microbiome plays a crucial role in maintaining overall health, and its influence on cardiovascular disease is becoming an area of intense research. This session will explore how the gut microbiota affects cardiovascular health through mechanisms such as modulation of inflammation, lipid metabolism, and blood pressure regulation. Specific microbial metabolites, including short-chain fatty acids, trimethylamine-N-oxide (TMAO), and bile acids, have been linked to the development of atherosclerosis, hypertension, and heart failure. We will discuss emerging evidence on the gut-heart axis and how gut symbiosis can exacerbate cardiovascular risk. Therapeutic strategies such as probiotics, prebiotics, dietary interventions, and fecal microbiota transplantation (FMT) will be explored for their potential to prevent or treat cardiovascular diseases. The session will highlight future opportunities for personalized cardiovascular medicine through microbiome modulation and the challenges in translating microbiome-based therapies into clinical practice.
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