Vascular Pharmacology: Focus on Endothelial Dysfunction

Endothelial dysfunction is a key early event in the development of cardiovascular diseases, influencing vascular tone, blood pressure regulation, and atherogenesis. This session will explore the molecular mechanisms driving endothelial dysfunction, including oxidative stress, inflammation, and impaired nitric oxide (NO) signaling. We will examine pharmacological approaches to restore endothelial function, such as nitric oxide donors, angiotensin receptor blockers (ARBs), statins, and emerging therapies targeting endothelial repair. The role of lifestyle interventions, such as diet and exercise, in mitigating endothelial dysfunction will also be discussed. Insights into novel drug candidates and therapeutic strategies will highlight future directions in vascular pharmacology aimed at preventing and treating cardiovascular diseases.

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