Targeting the Renin-Angiotensin-Aldosterone System (RAAS)
The Renin-Angiotensin-Aldosterone System (RAAS) plays a central role in regulating blood pressure, fluid balance, and cardiovascular homeostasis. Dysregulation of RAAS is a key contributor to hypertension, heart failure, and chronic kidney disease. This session will explore the latest advancements in RAAS-targeted therapies, including angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), aldosterone antagonists, and direct renin inhibitors. We will also examine the role of RAAS in modulating inflammation, fibrosis, and vascular remodeling. Newer therapeutic strategies, such as dual RAAS blockade and selective targeting of RAAS components, will be discussed, alongside clinical outcomes and safety considerations. The session will highlight how these therapies improve outcomes in patients with hypertension, heart failure, and related comorbidities.
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